Precision healthcare holds immense potential to transform disease prevention, diagnosis, and treatment by tailoring care to an individual’s genetic, environmental, and lifestyle factors. The majority of genomics research however, has been focused on populations of European ancestry, leaving under-represented and genetically diverse global populations, such as Indigenous Australians, underserved. This gap limits the generalisability of biomedical insights and exacerbates existing health inequities, but also limits the utility of language models that may have a significant impact on the way that genetic variants can be prioritised for drug discovery. In this talk, I describe some of the challenges associated with the analysis of Indigenous Australian genomes and discuss approaches that our team are using to develop precision approaches for primary healthcare in Australia.
Jimmy Breen
Black Ochre Data Labs (The Kids Research Institute Australia & Australian National University)
Improving precision healthcare for under-represented and genetically diverse global populations
Precision healthcare holds immense potential to transform disease prevention, diagnosis, and treatment by tailoring care to an individual’s genetic, environmental, and lifestyle factors. The majority of genomics research however, has been focused on populations of European ancestry, leaving under-represented and genetically diverse global populations, such as Indigenous Australians, underserved. This gap limits the generalisability of biomedical insights and exacerbates existing health inequities, but also limits the utility of language models that may have a significant impact on the way that genetic variants can be prioritised for drug discovery. In this talk, I describe some of the challenges associated with the analysis of Indigenous Australian genomes and discuss approaches that our team are using to develop precision approaches for primary healthcare in Australia.